Paediatric Haemato-Oncology & Bone Marrow Transplant (BMT)

Our department leverages our top-of-the-line technology and infrastructure to provide our paediatric patients with the best-in-class care. We boast the following advanced equipment and facilities: 

• Bone Marrow Transplantation (BMT) Unit: Our BMT unit provides comprehensive transplant services to patients with various conditions that require transplantation. The unit is equipped to perform allogeneic match-related, match-unrelated, and haploidentical transplants. Additionally, our dedicated nursing team, specially trained in the care of BMT patients, provides expert, compassionate support throughout the process. 

  Click here to know more about Bone Marrow Transplant

  Know more

• State-of-the-art operating theatres: Our operating theatres feature the latest surgical and diagnostic equipment. They are additionally equipped with laminar flow cabinets to maintain sterility and minimise the risk of post-surgical infection for your child. We, moreover, have dedicated isolation rooms for our immunocompromised patients.

• Sedation facilities for daycare procedures, such as bone marrow aspiration, biopsy, and lumbar puncture, so that your child can remain at ease during the procedure and then recover in the comfort of their own home.
• After completing rehabilitation therapy, including sessions in the paediatric rheumatology unit, we also provide a playroom to ensure your child is entertained and comfortable during treatment or their hospital stay.
• High-efficiency particulate air (HEPA)-filtered positive-pressure rooms: During the transplant procedure, our patients are accommodated in these rooms. The use of advanced technology and high air exchange rates ensures a safe environment with an exceptionally low risk of infection.

Our department specialises in the diagnosis and treatment of a wide range of haematological and/or malignant conditions in paediatric patients: 

• Childhood malignancies
  • Haematological malignancies: This includes blood cancers, such as leukaemia, lymphoma, which refers to cancer(s) in the lymphatic system, the network of organs, tissues, and vessels that help the body fight off infections, and multiple myeloma, which refers to cancer(s) forming in plasma cells, which produce antibodies to fight infections.
  • Childhood solid tumours, such as Wilms’ tumour,
  • Rhabdomyosarcoma
  • High-risk neuroblastoma
  • Bone cancers: Osteosarcoma, Ewing’s Sarcoma, Spindle Cell Sarcoma

• Anaemia: A condition characterised by the decreased ability of the blood to carry oxygen.
  • Iron-deficiency anaemia: Caused by iron insufficiency, due to which the red blood cells cannot produce enough amounts of haemoglobin, which helps red blood cells carry oxygen.
  • Vitamin deficiency anaemia: Caused by the presence of insufficient amounts of vitamin B12 and folate, which in turn, affects red blood cell function.
  • Aplastic anaemia: A rare and serious condition characterised by the inability of the bone marrow to produce enough red blood cells.
  • Haemolytic anaemia: Caused by red blood cells being destroyed faster than the bone marrow can produce new ones.

• Abnormalities in WBC counts: The WBC counts are abnormally high (leucocytosis) or low (leucopenia).
   
• Platelet abnormalities and bleeding/clotting disorders
  • Immune thrombocytopenic purpura: A condition in which the body’s immune system mistakenly attacks platelets, causing issues with blood clotting.
  • Haemophilia: A serious genetic condition characterised by a deficiency of clotting factors, which impairs blood clotting.
  • Von Willebrand disease: The most common genetic bleeding disorder, characterised by a deficiency of a protein called von Willebrand factor, which is crucial for clotting.
     
• Genetic conditions
  • Thalassaemia: Characterised by the inability of the body to produce normal haemoglobin.
  • Sickle cell disease: Characterised by the presence of abnormal haemoglobin, which in turn, results in red blood cells becoming rigid and sickle-shaped.

• Bone marrow disorders
  • Fanconi anaemia: A rare condition characterised by the inability of the bone marrow to produce healthy red blood cells and platelets.
  • Myeloproliferative disorders: A group of rare blood cancers characterised by the overproduction of red blood cells (polycythaemia vera), platelets (essential thrombocythaemia), and white blood cells (chronic myeloid leukaemia) by the bone marrow and scarring within the bone marrow (myelofibrosis).

• Amyloidosis: A rare disease characterised by the accumulation of abnormal proteins (amyloid) within organs, affecting their function.

   

• Immunodeficiency diseases
• Idiopathic autoimmune thrombocytopenia
• Hemophagocytic lymphohistiocytosis
• Other idiopathic blood disorders (unknown causes)